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You are here:Home » Antibodies » Abs to CD Markers » Anti -APRIL, blocking (Recombinant) (A Proliferation Inducing Ligand, TNFSF13, CD256, TALL-2)

Anti -APRIL, blocking (Recombinant) (A Proliferation Inducing Ligand, TNFSF13, CD256,
TALL-2)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Highly Purified E IP
APRIL is a cytokine that belongs to the TNF superfamily and binds to TACI and BCMA. It is implicated in the regulation of tumor cell growth and is involved in monocyte/macrophage-mediated immunological processes. Anti-APRIL (mouse) Monoclonal Antibody (recombinant) (Blocking) (APRY-1-1) is an antibody developed by antibody phage display technology using a human naive antibody gene library. These libraries consist of scFv (single chain fragment variable) composed of VH (variable domain of the human immunoglobulin heavy chain) and VL (variable domain of the human immunoglobulin light chain) connected by a polypeptide linker. The antibody fragments are displayed on the surface of filamentous bacteriophage (M13). This scFv was selected by affinity selection on antigen in a process termed panning. Multiple rounds of panning are performed to enrich for antigen-specific scFv-phage. Monoclonal antibodies are subsequently identified by screening after each round of selection. The selected monoclonal scFv is cloned into an appropriate vector containing a Fc portion of interest and then produced in mammalian cells to generate an IgG like scFv-Fc fusion protein.
Catalog #044562
ApplicationsSuitable for use in ELISA, Neutralization, Immunoprecipitation
Recommended DilutionOptimal dilutions to be determined by researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b,l
Clone NoApry-1-1
HostMouse
SourceMouse
Concentration1mg/ml
FormSupplied as a liquid in PBS, 10% glycerol, 0.02% sodium azide.
Purity>95% (SDS-PAGE)
ImmunogenMouse APRIL (aa 98-232).
SpecificityRecognizes mouse APRIL. Does not recognize mouse BAFF.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesA Proliferation Inducing Ligand, TNFSF13, CD256, TALL-2


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