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You are here:Home » Antibodies » Abs to Apoptosis, Caspase » Anti -Asc (Pycard, Target of Methylation-induced Silencing 1, TMS1, Caspase Recruitment Domain-containing Protein 5, Apoptosis-associated Speck-like Protein Containing CARD, CARD5)

Anti -Asc (Pycard, Target of Methylation-induced Silencing 1, TMS1, Caspase Recruitment
Domain-containing Protein 5, Apoptosis-associated Speck-like Protein Containing CARD,
CARD5)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP IH
Asc promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. It is a component of the inflammasome, a protein complex which also includes NLRP3/NALP3, CARD8 and CASP1 and whose function is the activation of proinflammatory caspases.
Catalog #044570
ApplicationsSuitable for use in mmunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Recommended DilutionOptimal dilutions to be determined by researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration1mg/ml
FormSupplied as a liquid in PBS, 10% glycerol, 0.02% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa at the N-terminal human Asc.
SpecificityRecognizes human and mouse Asc.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesPycard, Target of Methylation-induced Silencing 1, TMS1, Caspase Recruitment Domain-containing Protein 5, Apoptosis-associated Speck-like Protein Containing CARD, CARD5


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