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You are here:Home » Antibodies » Abs to Growth Factors, Cytokines » Anti -BAFF (BLyS, TALL-1, CD257, B Cell Activating Factor, TNFSF13B)

Anti -BAFF (BLyS, TALL-1, CD257, B Cell Activating Factor, TNFSF13B)

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Specifications

Clone Host Grade Applications
Monoclonal Rat Highly Purified E IP
BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren's syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).
Catalog #044578
ApplicationsSuitable for use in ELISA, Immunoprecipitation
Recommended DilutionOptimal dilutions to be determined by researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No2.81
HostRat
SourceHuman
Concentration1mg/ml
FormSupplied as a liquid in PBS, 10% glycerol, 0.02% sodium azide.
Purity>95% (SDS-PAGE)
ImmunogenHA-tagged human BAFF.
SpecificityRecognizes human BAFF.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesBLyS, TALL-1, CD257, B Cell Activating Factor, TNFSF13B


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