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You are here:Home » Molecular Biology » MB-CD Markers » BCMA, Recombinant, Mouse:Fc (B Cell Maturation Protein, CD269, TNFRSF17)

BCMA, Recombinant, Mouse:Fc (B Cell Maturation Protein, CD269, TNFRSF17)


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BCMA is a receptor for BAFF and APRIL. It promotes B cell survival and plays a role in the regulation of humoral immunity. It's downstream signaling is dependent on NF-kappaB and JNK.
Catalog #044596
Biological ActivityBlocks the binding of mouse BAFF and human APRIL to their receptors BCMA and TACI.
SequenceThe extracellular domain of mouse BCMA (aa 1-46) is fused at the C-terminus to the Fc portion of human IgG1.
Storage and StabilityShort-term Storage: +4°C
Long-term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C.
Molecular Weight~35kD (SDS-PAGE)
SourceHuman, Mouse, HEK 293 cells
Purity>95% (SDS-PAGE)
FormSupplied as a lyophilized powder from a 0.2um filtered solution in PBS pH 7.2.
SpecificityBinds mouse and human BAFF and APRIL.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesB Cell Maturation Protein, CD269, TNFRSF17

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