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You are here:Home » Molecular Biology » MB-CD Markers » BCMA, Recombinant, Mouse:Fc (B Cell Maturation Protein, CD269, TNFRSF17)

BCMA, Recombinant, Mouse:Fc (B Cell Maturation Protein, CD269, TNFRSF17)

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Specifications

BCMA is a receptor for BAFF and APRIL. It promotes B cell survival and plays a role in the regulation of humoral immunity. It's downstream signaling is dependent on NF-kappaB and JNK.
Catalog #044596
Human, mouse, HEK 293 cells. The extracellular domain of mouse BCMA (aa1-46) is fused at theC-terminus to the Flow Cytometry portion of human IgG1.
Biological ActivityBlocks the binding of mouse BAFF and human APRIL to their receptors BCMA and TACI.
SpecificityBinds mouse and human BAFF and APRIL.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~35kD (SDS-PAGE)
SourceHuman, Mouse, HEK 293 cells
Purity~95% (SDS-PAGE). Endotoxin: 0.01EU/ug (LAL)
Concentration1mg/ml
FormSupplied as a lyophilized powder from PBS. Reconstitute with 50ul sterile ddH2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesB Cell Maturation Protein, CD269, TNFRSF17


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