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You are here:Home » Biochemicals » Biochem-Inflammation » Bisindolylmaleimide I hydrochloride (GF 109203X, Gö 6850, BIM I)

Bisindolylmaleimide I hydrochloride (GF 109203X, Gö 6850, BIM I)


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Cell permeable kinase inhibitor with improved selectivity for protein kinase C (PKC) (Ki = 10 nM). Competitive inhibitor for the ATP-binding site of PKC. Anti-inflammatory. Binds to P-glycoprotein. Telomerase activity inhibitor. Potent glycogen synthase kinase-3 (GSK-3) inhibitor. Necrosis inhibitor. Blocks hERG potassium channels.
Catalog #044602
Storage and StabilityShort-term Storage: +4°C
Long-term Storage: -20°C
Stable for at least 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.
CAS Number176504-36-2
Molecular FormulaC25H24N4O2 . HCl
Molecular Weight412.5+36.5
Purity>98% (NMR)
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesGF 109203X, G? 6850, BIM I

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