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You are here:Home » Biochemicals » Biochem-Apoptosis » Bisindolylmaleimide IX methanesulfonate (Ro 31-8220, BIM IX)

Bisindolylmaleimide IX methanesulfonate (Ro 31-8220, BIM IX)


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Selective and cell permeable protein kinase C (PKC) inhibitor. Inhibits the stimulation of insulin secretion by glucose. Inhibits T cell activation. Apoptosis inducer. Potent glycogen synthase kinase-3 (GSK-3) inhibitor. Transcription inhibitor. Induces TNF receptor family-mediated cell death. Pim-1 kinase inhibitor. Antitumor compound.
Catalog #044606
Storage and StabilityShort-term Storage: +4°C
Long-term Storage: -20°C
Stable for at least 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.
CAS Number138489-18-6
Molecular FormulaC25H23N5O2S . CH4O3S
Molecular Weight457.6+96.1
Purity>98% (NMR)
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesRo 31-8220, BIM IX

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