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You are here:Home » Biochemicals » Biochem-Apoptosis » Bisindolylmaleimide VIII acetate (Ro 31-7549, BIM VIII)

Bisindolylmaleimide VIII acetate (Ro 31-7549, BIM VIII)


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Selective protein kinase C (PKC) inhibitor. Inhibits proliferation of cultured mouse epidermal keratinocytes. Enhances Fas- and TRAIL-mediated apoptosis. Inhibits T cell-mediated autoimmune diseases. Inhibits stimulation of insulin secretion by glucose. Inhibits panel of protein kinases (e.g. GSK-3beta, CDK2).
Catalog #044608
Storage and StabilityShort-term Storage: +4°C
Long-term Storage: -20°C
Stable for at least 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.
CAS Number138516-31-1
Molecular FormulaC24H22N4O2 . CH3COOH
Molecular Weight398.5+60.1
Purity>98% (NMR)
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesRo 31-7549, BIM VIII

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