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You are here:Home » Biochemicals » Biochem-Inflammation » BQ-123 sodium salt (Endothelin Receptor A Antagonist BQ-123, cyclo(-D-Trp-D-Asp-Pro-D-Val-Leu) . Na)

BQ-123 sodium salt (Endothelin Receptor A Antagonist BQ-123,
cyclo(-D-Trp-D-Asp-Pro-D-Val-Leu) . Na)

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Specifications

Potent and selective endothelin receptor A (ETA) antagonist. Suppresses the ET-1-induced decrease of LPL activity. Shows protective effects in ischemic acute renal failure. Neuroprotective. Anti-hypertensive. Inhibits ET-1 receptor binding and blocks Ca2+ mobilization, cellular contraction and MAP kinase activation. Cardiovascular agent. Reduces myocardial infarct size and oxidant injury.
Catalog #044617
Storage and StabilityShort-term Storage: +4°C
Long-term Storage: -20°C
Stable for at least 3 years after receipt when stored at -20°C.
CAS Number136553-81-6
Molecular FormulaC31H42N6O7 . Na
Molecular Weight609.7+23.0
Purity>98% (HPLC)
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesEndothelin Receptor A Antagonist BQ-123, cyclo(-D-Trp-D-Asp-Pro-D-Val-Leu) . Na


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