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You are here:Home » Molecular Biology » MB-Binding Proteins, Calcium » Calreticulin, Recombinant, Human (His) (CRP55, Calregulin, Endoplasmic Reticulum Resident Protein 60, ERp60, grp60)

Calreticulin, Recombinant, Human (His) (CRP55, Calregulin, Endoplasmic Reticulum Resident
Protein 60, ERp60, grp60)

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Specifications

Calreticulin is involved in regulation of intracellular Ca2+ homoeostasis and ER Ca2+ capacity. It constitutes together with calnexin and ERp57 the 'calreticulin/calnexin cycle' that is responsible for folding and quality control of newly synthesized glycoproteins. Calreticulin has been implicated to play a role in many biological systems, including functions inside and outside the ER, indicating that the protein is a multi-process molecule. Recently, Calreticulin was shown to enhance the merger of macrophages and tumor cells, increasing phagocytosis.
Catalog #044624
SequenceHuman calreticulin (aa18-417) is fused at the C-terminus to a His-tag.
Storage and StabilityShort-term Storage: +4°C
Long-term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C.
Molecular Weight~55kD (SDS-PAGE)
SourceHuman, E. coli
Purity>90% (SDS-PAGE)
Concentration0.3mg/ml
FormSupplied as a liquid from a 0.2um-filtered solution in 55mM TRIS-Cl, pH 8.2, 150mM NaCl.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCRP55, Calregulin, Endoplasmic Reticulum Resident Protein 60, ERp60, grp60


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