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CD137, Recombinant, Mouse:Fc (4-1BB, TNFRSF9)
CD137, Recombinant, Mouse:Fc (4-1BB, TNFRSF9)
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| CD137 (4-1BB) is a member of the tumor necrosis factor (TNF) receptor family. CD137 is expressed by activated T cells, dendritic cells, NK cells, granulocytes and cells of blood vessel walls at sites of inflammation. CD137 has costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. CD137 was shown to enhance immune activity to eliminate tumors in mice. | | | Catalog # | 044647 | | Sequence | The extracellular domain of mouse CD137 (aa 1-185) is fused at the C-terminus to the Fc portion of human IgG1. | | Storage and Stability | Short-term Storage: +4°C | | Long-term Storage: -20°C | | Working aliquots are stable for up to 3 months when stored at -20°C. | | Molecular Weight | ~50kD (SDS-PAGE) | | Source | Human, Mouse, HEK 293 cells | | Purity | >95% (SDS-PAGE) | | Concentration | 1mg/ml | | Form | 0.2um filtered solution in PBS. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | 4-1BB, TNFRSF9 |
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