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You are here:Home » Molecular Biology » MB-CD Markers » CD137:Fc, Recombinant, Human (4-1BB, TNFRSF9)

CD137:Fc, Recombinant, Human (4-1BB, TNFRSF9)

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Specifications

CD137 (4-1BB) is a member of the tumor necrosis factor (TNF) receptor family. CD137 is expressed by activated T cells, dendritic cells, NK cells, granulocytes and cells of blood vessel walls at sites of inflammation. CD137 has costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. CD137 was shown to enhance immune activity to eliminate tumors in mice.
Catalog #044648
SequenceThe cysteine-rich region of human CD137 (aa 1-186) is fused to the Fc portion of human IgG1.
Storage and StabilityShort-term Storage: +4°C
Long-term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C.
Molecular Weight~50kD (SDS-PAGE)
SourceHuman, HEK 293 cells
Purity>95% (SDS-PAGE)
Concentration1mg/ml
FormSupplied as a lyophilized powder from a 0.2um filtered solution in PBS pH 7.2.
SpecificityBinds to human CD137L (4-1BBL).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names4-1BB, TNFRSF9


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