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You are here:Home » Biochemicals » Biochem-Antibiotics » Colistin sulfate (USP Grade) (Polymyxin E, Belcomycin, Colimycin)

Colistin sulfate (USP Grade) (Polymyxin E, Belcomycin, Colimycin)


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Very potent polymyxin antibiotic. Has only one amino acid difference compared to polymyxin B. Antimicrobial. Targets the lipopolysaccharide (LPS) of the outer membrane of Gram-negative bacteria. Competitively displaces divalent cations (Ca2+ and Mg2+) from the negatively-charged phosphate groups LPS, causing disruption of the membrane. This increases the permeability of the cell envelope, leakage of cell contents, leading to apoptosis and cell death. Used against multidrug-resistant Gram-negative bacterial infections.
Catalog #044677
Storage and StabilityShort-term Storage: +4°C
Long-term Storage: +4°C
Stable for at least 2 years after receipt when stored at +4°C.
CAS Number1264-72-8
Molecular Formula2(C52H98N16O13) . 5(H2SO4)
Molecular Weight2801.7
PurityMixture (primarly colistin A and B).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesPolymyxin E, Belcomycin, Colimycin

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