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You are here:Home » Growth Factors, Cytokines » Growth Factors-TNF » DR6, Recombinant, Mouse:Fc (Death Receptor 6, Tumor Necrosis Factor Receptor Superfamily Member 21, TNFRSF21)

DR6, Recombinant, Mouse:Fc (Death Receptor 6, Tumor Necrosis Factor Receptor Superfamily
Member 21, TNFRSF21)

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Specifications

DR6 is an orphan TNF receptor superfamily member belonging to a subgroup of receptors called death receptors. Expressed ubiquitously with high expression in lymphoid organs, heart, brain, and pancreas. Broadly expressed by developing neurons where it functions as pro-apoptotic factor. Recently, it has been reported that interaction with the beta-amyloid precursor protein (APP) activates a widespread caspase-dependent self-destruction program dependent on caspase-6.
Catalog #044765
SequenceMouse DR6 (aa 42-348) is fused at the C-terminus to the Fc portion of human IgG1.
Storage and StabilityShort-term Storage: +4°C
Long-term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C.
Molecular Weight~80kD (SDS-PAGE)
SourceHuman, Mouse, HEK 293 cells
Purity>95% (SDS-PAGE)
Concentration1mg/ml
FormSupplied as a lyophilized powder from a 0.2um filtered solution in PBS pH 7.2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesDeath Receptor 6, Tumor Necrosis Factor Receptor Superfamily Member 21, TNFRSF21


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