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Fc:RANKL, Soluble, Recombinant, Mouse (TRANCE, ODF, OPGL, TNFSF11, CD254)
Fc:RANKL, Soluble, Recombinant, Mouse (TRANCE, ODF, OPGL, TNFSF11, CD254)
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| RANKL is an osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. Important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. RANKL plays an important role in the progression of Breast cancer. | | | Catalog # | 044789 | | Biological Activity | Induces osteoclastogenesis of bone marrow-derived macrophages. | | Sequence | Mouse RANKL (aa 157-316) is fused to at the N-terminus to the Fc portion of human IgG1. | | Storage and Stability | Short-term Storage: +4°C | | Long-term Storage: -20°C | | Stable for at least 6 months after receipt when stored at -20°C. | | Molecular Weight | ~55kD (SDS-PAGE) | | Source | Human, Mouse, HEK 293 cells | | Purity | >95% (SDS-PAGE) | | Concentration | 0.1mg/ml | | Form | Supplied as a lyophilized powder from a 0.2um filtered solution in PBS pH 7.2. | | Specificity | Binds to mouse RANK. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | TRANCE, ODF, OPGL, TNFSF11, CD254 |
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