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You are here:Home » Growth Factors, Cytokines » Growth Factors-FGF » FGF-19, Recombinant, Human (His) (Fibroblast Growth Factor 19)

FGF-19, Recombinant, Human (His) (Fibroblast Growth Factor 19)

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Specifications

FGF-19 (Fibroblast growth factor 19) is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. FGF-19 plays an important role in brain development during embryogenesis. FGF-19 binds only to FGF receptor 4 (FGFR4). Activity requires the presence of KLB.
Catalog #044795
Biological ActivityActivates ERK and FRS2alpha phosphorylation in rat hepatoma cells.
SequenceSignal peptide and human FGF-19 (aa 1-216) are fused at the C-terminus to a His-tag.
Storage and StabilityShort-term Storage: +4°C
Long-term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C.
Molecular Weight~28kD (SDS-PAGE)
SourceHuman, HEK 293 cells
Purity>90% (SDS-PAGE)
Concentration0.3mg/ml
FormSupplied as a liquid from a 0.2um-filtered solution in PBS, pH 7.2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesFibroblast Growth Factor 19


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