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You are here:Home » Growth Factors, Cytokines » Growth Factors-FGF » FGF-19:Fc, Recombinant, Human (Fibroblast Growth Factor 19)

FGF-19:Fc, Recombinant, Human (Fibroblast Growth Factor 19)

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Specifications

FGF-19 (Fibroblast growth factor 19) is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. FGF-19 plays an important role in brain development during embryogenesis. FGF-19 binds only to FGF receptor 4 (FGFR4). Activity requires the presence of KLB.
Catalog #044796
SequenceSignal peptide and human FGF-19 (aa 1-216) are fused at the C-terminus the Fc portion of human IgG1.
Storage and StabilityShort-term Storage: +4°C
Long-term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Molecular Weight~50kD (SDS-PAGE)
SourceHuman, HEK 293 cells
Purity>90% (SDS-PAGE)
FormSupplied as a lyophilized powder from a 0.2um-filtered solution in PBS, pH 7.2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesFibroblast Growth Factor 19


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