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You are here:Home » Molecular Biology » MB-Obesity Proteins » FTO, Recombinant, Human (His) (Fat Mass and Obesity-associated Protein, FATSO)

FTO, Recombinant, Human (His) (Fat Mass and Obesity-associated Protein, FATSO)

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Specifications

FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse 'fused toes' mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.
Catalog #044835
EndotoxinAs reported
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~65kD (SDS-PAGE)
SourceRecombinant protein corresponding to aa2-505 from human FTO, fused at the N-terminal to a His-tag, expressed in E. coli.
Purity~90% (SDS-PAGE)
Concentration~0.5mg/ml
FormSupplied as a liquid from a 0.2um-filtered solution in 55mM TRIS-Cl, pH 8.2, 150mM NaCl.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesFat Mass and Obesity-associated Protein, FATSO


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