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You are here:Home » Biochemicals » Biochem-Antibiotics » Heptelidic acid (Koningic acid, Avocettin, FO-4443, BRN 5091359)

Heptelidic acid (Koningic acid, Avocettin, FO-4443, BRN 5091359)


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Potent selective glyceraldehyde 3-phosphate dehydrogenase (GAPDH) inhibitor. Binds to the essential Cys149 residue in the catalytic site of GADPH.
Anticancer compound. Selectively kills high-glycolytic cancer cells through glucose-dependent active ATP deprivation.
Apoptosis inhibitor. DNA fragmentation and caspase-3 activation inhibitor.
Selective and competitive inhibitor of mammalian DNA polymerases beta, lambda and terminal deoxynucleotidyl transferase (TdT) in family X of pols.
Catalog #044883
Storage and StabilityShort-term Storage: +4°C
Long-term Storage: -20°C
Stable for at least 3 years after receipt when stored at -20°C.
CAS Number74310-84-2
Molecular FormulaC15H20O5
Molecular Weight280.3
Purity>95% (HPLC)
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesKoningic acid, Avocettin, FO-4443, BRN 5091359

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