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You are here:Home » Antibodies » Abs to Membrane Proteins » Anti -IGFLR1 (IGF-like Family Receptor 1, Transmembrane Protein 149, TMEM149, U2 Small Nuclear RNA Auxiliary Factor 1-like 4)

Anti -IGFLR1 (IGF-like Family Receptor 1, Transmembrane Protein 149, TMEM149, U2 Small
Nuclear RNA Auxiliary Factor 1-like 4)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B FC
Insulin-growth factor-like gene family is a new family of proteins consisting of four proteins in humans (IGFL1 to 4) and one in mice (mIGFL). mIGFL is expressed in normal skin in mice and further upregulated during inflammation responses in skin or after skin wounding. In human only IGFL1 expression is increased in psoriatic skin samples. Mouse IGFL and human IGFL1 and 3 interact with specificity and high affinity to a novel receptor named IGF-like family receptor 1 (formerly TMEM-149). Analysis of the amino acid sequence of IGFLR1 indicated that this receptor is likely a novel member of the TNFR family. IGFLR1 is expressed most abundantly on mouse T cells, suggesting that mIGFL and IGFL1 produced in the skin may potentially exert regulatory functions on T cell responses.
Catalog #044899
ApplicationsSuitable for use in Flow Cytometry, Western Blot
Recommended DilutionOptimal dilutions to be determined by researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration1mg/ml
FormSupplied as a liquid in PBS, 10% glycerol, 0.02% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenRecombinant human IGFLR1 (aa 23-154).
SpecificityRecognizes human IGFLR1. Does not recognize mouse IGFLR1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesIGF-like Family Receptor 1, Transmembrane Protein 149, TMEM149, U2 Small Nuclear RNA Auxiliary Factor 1-like 4


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