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You are here:Home » Molecular Biology » Growth Factors-Interleukin » IL-17A:Fc, Recombinant, Human (Interleukin-17A, Cytotoxic T-lymphocyte-associated Antigen 8, CTLA-8)

IL-17A:Fc, Recombinant, Human (Interleukin-17A, Cytotoxic T-lymphocyte-associated Antigen
8, CTLA-8)

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Specifications

Interleukin-17A (IL-17A) exhibits multiple biological activities on a variety of cells including the induction of IL-6 and IL-8 production in fibroblsts, the enhancement of surface expression of ICAM-1 in fibroblast, activation of NF-kappaB and costimulation of T cell proliferation. Induces stromal cells to produce proinflammatory and hematopoietic cytokines.
Catalog #044904
SequenceSignal peptide and the sequence of human IL-17A (aa 1-155) are fused at the C-terminus to the Fc portion of human IgG1.
Storage and StabilityShort-term Storage: +4°C
Long-term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C.
Molecular Weight~45kD (SDS-PAGE)
SourceHuman, HEK 293 cells
Purity>90% (SDS-PAGE)
FormSupplied as a liquid from a 0.2um-filtered solution in PBS, pH 7.2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesInterleukin-17A, Cytotoxic T-lymphocyte-associated Antigen 8, CTLA-8


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