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You are here:Home » Antibodies » Abs to Interleukin » Anti -IL-23p19 (Interleukin-23 Subunit p19, Interleukin-23 Subunit alpha, IL-23-A)

Anti -IL-23p19 (Interleukin-23 Subunit p19, Interleukin-23 Subunit alpha, IL-23-A)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
IL-23p19 associates with IL-12b to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 binds to an heterodimeric receptor complex composed of IL-12RB1 and IL-23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
Catalog #044915
ApplicationsSuitable for use in ELISA, Western Blot
Recommended DilutionOptimal dilutions to be determined by researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceMouse
Concentration1mg/ml
FormSupplied as a liquid in 0.2um-filtered PBS, pH 7.4. No preservative added.
PurityPurified by Protein A affinity chromatography.
ImmunogenRecombinant mouse IL-23p19.
SpecificityRecognizes mouse IL-23p19. Detects a band of ~23kD by Western blot. Cross-reacts with human IL-23p19. Does not cross-react with human IL23p40.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesInterleukin-23 Subunit p19, Interleukin-23 Subunit alpha, IL-23-A


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