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You are here:Home » Antibodies » Abs to Interleukin » Anti -IL-23p40 (Interleukin-23 Subunit p40, IL-23 Subunit p40, Interleukin-12 Subunit beta, IL-12B, Cytotoxic Lymphocyte Maturation Factor 40kD Subunit, CLMF p40, IL-12 Subunit p40, NK Cell Stimulatory Factor Chain 2, NKSF2)

Anti -IL-23p40 (Interleukin-23 Subunit p40, IL-23 Subunit p40, Interleukin-12 Subunit
beta, IL-12B, Cytotoxic Lymphocyte Maturation Factor 40kD Subunit, CLMF p40, IL-12 Subunit
p40, NK Cell Stimulatory Factor Chain 2, NKSF2)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
IL-23p40 associates with IL-23A to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 binds to an heterodimeric receptor complex composed of IL-12RB1 and IL-23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. Defects in IL-23p40 are a cause of mendelian susceptibility to mycobacterial disease (MSMD). Genetic variations in IL-23p40 are a cause of susceptibility to psoriasis type 11 (PSORS11).
Catalog #044916
ApplicationsSuitable for use in ELISA, Western Blot
Recommended DilutionOptimal dilutions to be determined by researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone NoI 1108
HostMouse
SourceHuman
Concentration1mg/ml
FormSupplied as a liquid in 0.2um-filtered PBS, pH 7.4. No preservative added.
PurityPurified by Protein A affinity chromatography.
ImmunogenRecombinant human IL-23p40.
SpecificityRecognizes human IL-23p40. Does not cross-react with human IL-23p19.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesInterleukin-23 Subunit p40, IL-23 Subunit p40, Interleukin-12 Subunit beta, IL-12B, Cytotoxic Lymphocyte Maturation Factor 40 kDa Subunit, CLMF p40, IL-12 Subunit p40, NK Cell Stimulatory Factor Chain 2, NKSF2


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