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You are here:Home » Biochemicals » Biochem-Antibiotics » Lactacystin

Lactacystin

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Specifications

Induces neuritogenesis. Potent and selective irreversible proteasome inhibitor. Specifically inhibits 20S proteasome (MCP; multicatalytic complex). Blocks proteasome activity by targeting the catalytic beta-subunit. Apoptosis inducer. Anticancer compound. Upregulates HSP70 and HSP22. Induces differentiation and inhibits cell cycle progression in several tumor cell lines. Inhibits NF-kappaB activation by inhibiting IkappaB degradation. Cathepsin A inhibitor. gamma-Secretase activity inhibitor. Anti-adipogenic.
Catalog #044983
Storage and StabilityShort-term Storage: +4°C
Long-term Storage: -20°C
Stable for at least 3 years after receipt when stored at -20°C.
CAS Number133343-34-7
Molecular FormulaC15H24N2O7S
Molecular Weight376.4
Purity>98% (HPLC)
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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