Lariatin A CAS 732286-09-8

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044996 Lariatin A CAS: 732286-09-8

Specifications

References

CAS Number

732286-09-8

Grade

Highly Purified

Molecular Formula

C94H143N27O25

Molecular Weight

2051.4

EU Commodity Code

38220090

Shipping Temp

Storage Temp

-20°C

Peptide with lasso structure. Antimycobacterial.

CAS Number

732286-09-8

Source

Rhodococcus jostii

Molecular Weight

2051.4

Sequence

H-Gly-Ser-Gln-Leu-Val-Tyr-Arg-Glu-Trp-Val-Gly-His-Ser-Asn-Val-Ile-Lys-Pro-OH

Molecular Formula

C94H143N27O25

Solubility

Methanol or water

Appearance

Supplied as an off-white solid.

Purity

≥95% (HPLC)

Storage and Stability

Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Important Note

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Toxicity and Hazards

All products should be handled by qualified personnel only, trained in laboratory procedures.

References

1. Lariatins, antimycobacterial peptides produced by Rhodococcus sp. K01-B0171, have a lasso structure: M. Iwatsuki, et al.; JACS 128, 7486 (2006)|2. Lariatins, novel anti-mycobacterial peptides with a lasso structure, produced by Rhodococcus jostii K01-B0171: M. Iwatsuki, et al.; J. Antibiot. (Tokyo) 60, 357 (2007)|3. Lys17 in the 'lasso' peptide lariatin A is responsible for anti-mycobacterial activity: M. Iwatsuki, et al.; Bioorg. Med. Chem. Lett. 19, 2888 (2009)|4. Molecular cloning of the gene cluster for lariatin biosynthesis of Rhodococcus jostii K01-B0171: J. Inokoshi, et al.; Appl. Microbiol. Biotechnol. 95, 451 (2012)