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You are here:Home » Biochemicals » Biochem-Apoptosis » Latrunculin A (LAT-A, NSC 613011)

Latrunculin A (LAT-A, NSC 613011)

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Specifications

Catalog #044997
A cell-permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 11 complex with monomeric G-actin. Depolymerizes actin filaments (F-actin) and acts as a phagocytosis inhibitor. Anticancer compound. Suppresses hypoxia-induced HIF-1 activation in tumor cells. Inhibits tumor cell invasion.
SolubilityDMSO, Ethanol
Molecular Weight~421.55
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number76343-93-6
Molecular FormulaC22H31NO5S
Molecular Weight421.6
SourceLatrunculia magnifica
Purity>96 (HPLC)
FormSupplied as a white solid
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesLAT-A, NSC 613011


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