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044997 Latrunculin A (LAT-A, NSC 613011) CAS: 76343-93-6

Specifications
CAS Number
76343-93-6
Grade
Highly Purified
Molecular Formula
C22H31NO5S
Molecular Weight
421.6
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
LAT-A, NSC 613011

A cell-permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin. Depolymerizes actin filaments (F-actin) and acts as a phagocytosis inhibitor. Anticancer compound. Suppresses hypoxia-induced HIF-1 activation in tumor cells. Inhibits tumor cell invasion

CAS No.
76343-93-6
Solubility
DMSO (25mg/ml), Ethanol (25mg/ml).
Molecular Weight
421.55
Method for Determining Identity
Proton NMR
Purity
≥97% (HPLC)
Appearance
Colorless viscous film
Storage and Stability
Lyophilized powder is stable for 6 months after receipt at -20°C.
Source
Latrunculia magnifica
Purity
≥97% (HPLC)
Form
Colorless viscous film
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
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