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Specifications

Catalog #	044997
A cell-permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1	1 complex with monomeric G-actin. Depolymerizes actin filaments (F-actin) and acts as a phagocytosis inhibitor. Anticancer compound. Suppresses hypoxia-induced HIF-1 activation in tumor cells. Inhibits tumor cell invasion.
Solubility	DMSO, EtOH
Molecular Weight	~421.55
Storage and Stability	Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	76343-93-6
Molecular Formula	C22H31NO5S
Molecular Weight	421.6
Purity	>96 (HPLC)
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names	LAT-A, NSC 613011