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You are here:Home » Biochemicals » Biochem-Inflammation » LY-333,531 hydrochloride (Ruboxistaurin)

LY-333,531 hydrochloride (Ruboxistaurin)


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Isozyme selective inhibitor of protein kinase Cbeta (PKCbeta).
PKCbetaI and PKCbetaII isozyme inhibitor.
Amelioriates diabetic retinopathy, diabetic peripheral neuropathy and diabetic nephropathyAnti-cancer and anti-angiogenic compound.
Suppresses glucose-induced adhesion of human monocytes to endothelial cells.
Suppresses ERK1/2 and Akt phosphorylation.
Catalog #045028
Storage and StabilityShort-term Storage: +4°C
Long-term Storage: -20°C
Stable for at least 2 years after receipt when stored at -20°C.
CAS Number169939-93-9
Molecular FormulaC28H28N4O3 . HCl
Molecular Weight468.6+36.5
Purity>98% (NMR)
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesRuboxistaurin

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