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You are here:Home » Antibodies » Abs to Transcription Factors, Notch » Anti -Notch1 (Neurogenic Locus Notch Homolog Protein 1, Motch A, mT14, p300)

Anti -Notch1 (Neurogenic Locus Notch Homolog Protein 1, Motch A, mT14, p300)

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Specifications

Clone Host Grade Applications
Monoclonal Rat Highly Purified FC
Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signaling is also involved in cellular processes through-out adulthood. Signaling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins.
Catalog #045098
ApplicationsSuitable for use in Flow Cytometry
Recommended DilutionOptimal dilutions to be determined by researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a,k
Clone No22E5
HostRat
SourceMouse
Concentration1mg/ml
FormSupplied as a liquid in PBS, 10% glycerol, 0.02% sodium azide.
Purity>95% (SDS-PAGE)
ImmunogenRecombinant mouse Notch1:Fc (AG-40B-0109).
SpecificityRecognizes endogenous mouse Notch-1 receptor.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesNeurogenic Locus Notch Homolog Protein 1, Motch A, mT14, p300


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