Potent CDK1/cyclin B (IC50 = 9.5nM) and CDK2/cyclin A3 (IC50 = 5.4nM) inhibitor. 1,000-fold more potent than NU2058. Selective for CDK1 and CDK2 compared to CDK4/D1 (IC50 = 1.6uM), DYRK1A (IC50 = 0.9uM), PDK1 (IC50 = 0.8uM) and ROCKII (IC50 = 0.6uM). Inhibits cell growth.
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