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You are here:Home » Antibodies » Abs to Obesity Proteins » Anti -Obestatin

Anti -Obestatin

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E
Obestatin derives like ghrelin from proghrelin, but exhibits opposite physiological effects. Obestatin decreases food intake and body weight in rodents. Moreover, obestatin also counteracts ghrelin's effect by decelerating gastric emptying and decreasing intestinal contractility. Obestatin binds to orphan G protein-coupled receptor GPR39. Amidation of the C-terminus seems to be important for obestatin's activity.
Catalog #045111
ApplicationsSuitable for use in ELISA
Recommended DilutionOptimal dilutions to be determined by researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration1mg/ml
FormSupplied as a liquid in 0.2um-filtered PBS, pH 7.4. No preservative added.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa 76-98 (F76NAPFDVGIKLSGVQYQQHSQAL98) of human obestatin.
SpecificityRecognizes human obestatin. Cross-reacts with mouse obestatin.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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