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PD 184,352 (2-(2-Chloro-4-iodo-phenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide, CI-1040)
PD 184,352 (2-(2-Chloro-4-iodo-phenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide,
CI-1040)
Pricing
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| MEK (MAPKK) inhibitor. Potent and selective MAPK (ERK kinase 1; MEK1) activation inhibitor (IC50 = 300 nM in vitro, IC50 = 2 nM in vivo). Suppresses activation of MAPK but does not block its activity. Antiproliferative. Causes cell-cycle arrest in G1 phase. Tumor suppressor. Apoptosis inducer. | | | Catalog # | 045129 | | Storage and Stability | Short-term Storage: +4°C | | Long-term Storage: -20°C | | Stable for at least 2 years after receipt when stored at -20°C. | | CAS Number | 212631-79-3 | | Molecular Formula | C17H14ClF2IN2O2 | | Molecular Weight | 478.7 | | Purity | >95% (HPLC, NMR) | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | 2-(2-Chloro-4-iodo-phenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide, CI-1040 |
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