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You are here:Home » Biochemicals » Biochem-Antibiotics » (R,R)-Hymeglusin (1233A, F-244, L-659-699)

(R,R)-Hymeglusin (1233A, F-244, L-659-699)


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beta-Lactone antibiotic. Antibacterial and antifungal. Specific and irreversible inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase in vitro and in vivo by covalently modifying the active Cys129 residue of the enzyme. Mevalonate biosynthesis inhibitor.
Catalog #045186
SourceIsolated from fungal strain Scopulariopsis sp. F-244.
SolubilitySoluble in methanol, ethanol, DMSO, chloroform or ethyl acetate. Insoluble in water or hexane.
Storage and StabilityShort-term Storage: +4°C
Long-term Storage: -20°C
Stable for at least 3 years after receipt when stored at -20°C.
CAS Number29066-42-0
Molecular FormulaC18H28O5
Molecular Weight324.40
SourceScopulariopsis sp. F-244
Purity95% (HPLC)
FormWhite to off-white solid
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names1233A, F-244, L-659-699

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