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You are here:Home » Molecular Biology » MB-Resistin » Resistin, Recombinant, Human (FIZZ3, Found in Inflammatory Zone 3, ADSF, Adipose Tissue-Specific Secretory Factor)

Resistin, Recombinant, Human (FIZZ3, Found in Inflammatory Zone 3, ADSF, Adipose
Tissue-Specific Secretory Factor)

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Specifications

The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM; RELM-alpha/FIZZ 1 and RELM-beta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.
Catalog #045246
Biological ActivityInhibits insulin-stimulated glucose uptake in L6 skeletal muscle cells.
SequenceHuman resistin (aa 20-108) is fused at the N-terminus to a FLAG®-tag.
Storage and StabilityShort-term Storage: +4°C
Long-term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C.
Molecular Weight~12kD (SDS-PAGE)
SourceHuman, HEK 293 cells
Purity>90% (SDS-PAGE)
Concentration0.5mg/ml
FormSupplied as a 0.2um-filtered solution in PBS, pH 7.2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesFIZZ3, Found in Inflammatory Zone 3, ADSF, Adipose Tissue-Specific Secretory Factor


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