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You are here:Home » Molecular Biology » MB-Sirtuins » Sirtuin 1, Recombinant, Mouse (His) (Sirt1, NAD-dependent Deacetylase Sirtuin-1, SIR2-like Protein 1, SIR2alpha, Sir2l7)

Sirtuin 1, Recombinant, Mouse (His) (Sirt1, NAD-dependent Deacetylase Sirtuin-1, SIR2-like
Protein 1, SIR2alpha, Sir2l7)

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Specifications

Sirtuin 1 (SIRT1) is a NAD-dependent protein deacetylase, which regulates processes such as apoptosis and muscle differentiation by deacetylating key proteins. Sirtuin 1 emerged as critical regulator of longevity and aging in several model organisms. Furthermore, a variety of age-associated diseases such as type 2 diabetes, obesity, osteoporosis, and Alzheimer's disease are associated with sirtuins. Sirtuin 1 has been suggested as potential biomarker for tumorigenesis.
Catalog #045290
SequenceMouse sirtuin 1 (aa 2-737) is fused at the N-terminus to a His-tag.
Storage and StabilityShort-term Storage: +4°C
Long-term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C.
Molecular Weight~100kD (SDS-PAGE)
SourceMouse, E. coli
Purity>90% (SDS-PAGE)
FormSupplied as a liquid from a 0.2um-filtered solution in 55mM TRIS-Cl, pH 8.2, 150mM NaCl.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesSirt1, NAD-dependent Deacetylase Sirtuin-1, SIR2-like Protein 1, SIR2alpha, Sir2l7


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