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You are here:Home » Antibodies » Abs to Sirtuins » Anti -Sirtuin 6 (SIRT6, , NAD-dependent Deacetylase Sirtuin-6, Mono-ADP-ribosyltransferase Sirtuin 6, SIR2-like Protein 6, SIR2L6)

Anti -Sirtuin 6 (SIRT6, , NAD-dependent Deacetylase Sirtuin-6, Mono-ADP-ribosyltransferase
Sirtuin 6, SIR2-like Protein 6, SIR2L6)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Sirtuin-6 is a NAD-dependent protein deacetylase with activity towards 'Lys-9' and 'Lys-56' of histone H3. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Required for genomic stability and for normal IGF1 serum levels and normal glucose homeostasis. Modulates cellular senescence and apoptosis. Regulates the production of TNF protein.
Catalog #045300
ApplicationsSuitable for use in ELISA, Western Blot
Recommended DilutionOptimal dilutions to be determined by researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration1mg/ml
FormSupplied as a liquid in 0.2um-filtered PBS, pH 7.4. No preservative added.
PurityPurified by Protein A affinity chromatography.
ImmunogenRecombinant human sirtuin 6.
SpecificityRecognizes human sirtuin 6. Detects a band of ~42kD by Western blot.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesSIRT6, , NAD-dependent Deacetylase Sirtuin-6, Mono-ADP-ribosyltransferase Sirtuin 6, SIR2-like Protein 6, SIR2L6


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