Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Molecular Biology » MB-Sirtuins » Sirtuin 6, Recombinant, Human (His) (SIRT6, , NAD-dependent Deacetylase Sirtuin-6, Mono-ADP-ribosyltransferase Sirtuin 6, SIR2-like Protein 6, SIR2L6)

Sirtuin 6, Recombinant, Human (His) (SIRT6, , NAD-dependent Deacetylase Sirtuin-6,
Mono-ADP-ribosyltransferase Sirtuin 6, SIR2-like Protein 6, SIR2L6)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Sirtuin 6 (SIRT6) is a NAD-dependent protein deacetylase with activity towards 'Lys-9' and 'Lys-56' of histone H3. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Required for genomic stability and for normal IGF1 serum levels and normal glucose homeostasis. Modulates cellular senescence and apoptosis. Regulates the production of TNF protein.
Catalog #045301
SequenceHuman sirtuin 6 (aa 1-355) is fused at the N-terminus to a His-tag.
Storage and StabilityShort-term Storage: +4°C
Long-term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C.
Molecular Weight~45kD (SDS-PAGE)
SourceHuman, E. coli
Purity>90% (SDS-PAGE)
Concentration~0.5mg/ml
FormSupplied as a liquid from a 0.2um-filtered solution in 55mM TRIS-Cl, pH 8.2, 150mM NaCl.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesSIRT6, , NAD-dependent Deacetylase Sirtuin-6, Mono-ADP-ribosyltransferase Sirtuin 6, SIR2-like Protein 6, SIR2L6


External Links