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You are here:Home » Biochemicals » Biochem-Apoptosis » Swinholide A

Swinholide A


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Cell permeable dimeric dilactone macrolide.
Cytotoxic compound.
Specific actin filament (F-actin) inhibitor. Disrupts the actin cytoskeleton by sequestering actin dimers and rapidly severing actin filaments (F-actin).
Depolymerizes actin filaments (F-actin).
Apoptosis inducer.
Alterates the actin cytoskeleton of GH4 cells and inhibits insulin-increased prolactin gene transcription.
Catalog #045320
Storage and StabilityShort-term Storage: +4°C
Long-term Storage: -20°C
Stable for at least 2 years after receipt when stored at -20°C.
CAS Number95927-67-6
Molecular FormulaC78H132O20
Molecular Weight1389.9
Purity>97% (HPLC)
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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