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You are here:Home » Molecular Biology » MB-Protein Kinases » AKAP7, Recombinant, Human, aa1-81, His-Tag (A-kinase Anchor Protein 7 Isoforms alpha and beta, AKAP-7 Isoforms alpha and beta, Protein Kinase A-anchoring Protein 7 Isoforms alpha/beta, A-kinase Anchor Protein 18kD, AKAP 18, AKAP18)

AKAP7, Recombinant, Human, aa1-81, His-Tag (A-kinase Anchor Protein 7 Isoforms alpha and
beta, AKAP-7 Isoforms alpha and beta, Protein Kinase A-anchoring Protein 7 Isoforms
alpha/beta, A-kinase Anchor Protein 18kD, AKAP 18, AKAP18)

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Specifications

AKAP7 (A-kinase anchor protein 7 isoform gamma isoform alpha) , also known as AKAP18, belongs to the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAP 7 is expressed in brain, heart, lung, pancreas and skeletal muscle. AKAP 7 binds PKA to the plasma membrane, and permits functional coupling to the L-type calcium channel.
Catalog #045404
SourceRecombinant corresponding to aa1-81 from human AKAP7, fused to His-tag at N-terminus, expressed in E.coli.
Molecular Weight~11.5kD (105aa) confirmed by MALDI-TOF
AA SequenceMGSSHHHHHH SSGLVPRGSH MGSHMGQLCC FPFSRDEGKI SEKNGGEPDD AELVRLSKRL VENAVLKAVQ QYLEETQNKN KPGEGSSVKT EAADQNGNDN ENNRK
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~11.5kD
SourceE.coli
Purity~90% (SDS-PAGE)
Concentration~1mg/ml
FormSupplied as a liquid in 20mM Tris-HCl, pH 8.0, 1mM DTT, 50mM sodium chloride, 10% glycerol.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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