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You are here:Home » Antibodies » Abs to Catenin » Anti -Catenin, alpha T (alpha T-Catenin, a-T-Catenin, Catenin (Cadherin Associated Protein) alpha 3, Catenin alpha-3, Ctnna3, VR22)

Anti -Catenin, alpha T (alpha T-Catenin, a-T-Catenin, Catenin (Cadherin Associated
Protein) alpha 3, Catenin alpha-3, Ctnna3, VR22)

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B
Alpha-catenins stabilize the cell-cell contacts by functioning as a molecular switch that regulates actin dynamics at the site of the adherens junction (1). Alpha-T Catenin is involved in the formation of stretch-resistant cell-cell adhesion complexes (2). Alpha-T catenin is expressed predominantly in cardiomyocytes, where it colocalizes with alpha-E catenin at the intercalated discs (1). Moreover, alpha-T Catenin is also expressed in the brain and inhibits Wnt signaling, so it is implicated in Alzheimer’s disease (3).
Catalog #045547
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000-10,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
Clone No13C19
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in PBS, sodium azide, BSA, glycerol.
PuritySupernatant
ImmunogenSynthetic peptide corresponding to residues in human Alpha-T Catenin.
SpecificityRecognizes human Alpha-T Catenin.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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