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You are here:Home » Antibodies » Abs to Chromatin Proteins » Anti -BAF57 (SMARCE1, FLJ35648, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1, BRG1-associated factor 57)

Anti -BAF57 (SMARCE1, FLJ35648, SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin subfamily E member 1, BRG1-associated factor 57)

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IP IH IC
BAF57 is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for activation of proteins normally repressed by chromatin. It, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. BAF57 contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, BAF57 has no yeast counterpart (1).
Catalog #045565
ApplicationsSuitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000-10,000
Immunohistochemistry: 1:100-250
Immunocytochemistry: 1:100-250
Immunoprecipitation: 1:10-100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
Clone No13C13
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in PBS, sodium azide, BSA, glycerol.
PuritySupernatant
ImmunogenSynthetic peptide corresponding to residues in human BAF57.
SpecificityRecognizes human BAF57. Species sequence homology: Mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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