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You are here:Home » Antibodies » Abs to Actin Related Proteins » Anti -BAF53 (ACTL6A, ACTL6, ARPN-BETA, Arp4, BAF53A, INO80K, MGC5382, Actin-like protein 6A, INO80 complex subunit K)

Anti -BAF53 (ACTL6A, ACTL6, ARPN-BETA, Arp4, BAF53A, INO80K, MGC5382, Actin-like protein
6A, INO80 complex subunit K)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IP IH IC
BAF53 is a family member of actin-related proteins (ARPs) that share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. BAF53 is a 53kD subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate activation of specific proteins by antagonizing chromatin-mediated repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1 and the association of the BAF complex with chromatin/matrix (1).
Catalog #045578
ApplicationsSuitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry, and Immunocytochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000-10,000
Immunohistochemistry: 1:50-100
Immunocytochemistry: 1:100-250
Immunoprecipitation: 1:10-100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
Clone No13C12
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in PBS, sodium azide, BSA, glycerol.
PuritySupernatant
ImmunogenSynthetic peptide corresponding to residues in human BAF53.
SpecificityRecognizes human BAF53. Species sequence homology: Mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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