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You are here:Home » Antibodies » Abs to Signal Transduction » Anti -SRP19 (Signal recognition particle 19kD protein)

Anti -SRP19 (Signal recognition particle 19kD protein)

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IP IH IC
SRP19 is an RNA-binding component of the Signal recognition particle (SRP), consisting of a 7S RNA molecule of 300 nucleotides and six protein subunits (SRP72, SRP68, SRP54, SRP19, SRP14, and SRP9), and it plays a role in the assembly of SRP (1, 2). It interacts with the major groove of the helix 6 tetraloop and the minor groove of the helix 8 tetraloop, and it clamps the tetraloops of two branched helices in the S-domain of SRP RNA (1). SRP19 is also directly bound and efficiently imported into the nuclei in vitro by two members of the importin beta family of transport receptors, importin 8 and transportin (3).
Catalog #045601
ApplicationsSuitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry, and Immunocytochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:10,000-50,000
Immunohistochemistry: 1:100-250
Immunocytochemistry: 1:100-250
Immunoprecipitation: 1:10-100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
Clone No13C119
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in PBS, sodium azide, BSA, glycerol.
PuritySupernatant
ImmunogenSynthetic peptide corresponding to residues in human SRP19.
SpecificityRecognizes human SRP19. Species sequence homology: Mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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