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You are here:Home » Antibodies » Abs to Hormones, Steroids » Anti -CGB (CGB8, Choriogonadotropin subunit beta, Chorionic gonadotrophin chain beta)

Anti -CGB (CGB8, Choriogonadotropin subunit beta, Chorionic gonadotrophin chain beta)

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant IH
Human chorionic gonadotropin beta (CGB) belongs to the glycoprotein hormone family that includes the beta subunit of lutenizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) (1). These hormones are central to the endocrine system that regulates normal growth, sexual development, and reproductive function (2). HCG primarily maintains the myometrial and decidual spiral arteries, or the vascular supply of the placenta during the full course of pregnancy (3). It is mainly secreted by the endocrine villous cytotrophoblasts into the maternal compartment and stimulates the formation of the syncytiotrophoblast in an autocrine manner (4). Then HCG binds to the corpus luteum of the ovary, which is stimulated to produce progesterone and maintain the secretory endometrium (5). CGB confers biological specificity, whereas the alpha subunit of HCG is common to all glycoprotein hormones (1).
Catalog #045609
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry: 1:100-250
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
Clone No13C27
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in PBS, sodium azide, BSA, glycerol.
PuritySupernatant
ImmunogenHuman CGB protein.
SpecificityRecognizes human CGB.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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