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You are here:Home » Antibodies » Abs to Cathepsin » Anti -Cathepsin L1 (CTSL1 antibody, CATL antibody, CTSL, FLJ31037 antibody, MEP antibody, Cathepsin L1 light chain antibody, Major excreted protein antibody)

Anti -Cathepsin L1 (CTSL1 antibody, CATL antibody, CTSL, FLJ31037 antibody, MEP antibody,
Cathepsin L1 light chain antibody, Major excreted protein antibody)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IH
Cathepsin L1 is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha- 1 protease inhibitor, a major controlling element of neutrophil elastase activity. Cathepsin L1 has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor (1).
Catalog #045611
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000-10,000
Immunohistochemistry: 1:50-100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
Clone NoEPR8011
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in PBS, sodium azide, BSA, glycerol
PuritySupernatant
ImmunogenSynthetic peptide corresponding to residues in human Cathepsin L1.
SpecificityRecognizes human Cathepsin L1. Species Crossreactivity: Mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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