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You are here:Home » Antibodies » Abs to Enzymes, Deacetylase » Anti -Histone Deacetylase 6 (HDAC6, FLJ16239, HD6)

Anti -Histone Deacetylase 6 (HDAC6, FLJ16239, HD6)

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IP IH IC
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone Deacetylase 6 belongs to the class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains, which appear to function independently of each other. Histone Deacetylase 6 possesses histone deacetylase activity and represses transcription.
Catalog #045628
ApplicationsSuitable for use in Western Blot, Immunocytochemistry, Immunoprecipitation and Immunohistochemistry. Other applications have not been tested.
Recommended Dilutions
Western Blot: 1:10,000-1:50,000
Immunohistochemistry: 1:50-1:100
Immunocytochemistry: 1:500-1:1000
Immunoprecipitation: 1:10-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
Clone NoEPR1698(2)
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in PBS, pH 7.2, 0.05% BSA, 0.01% sodium azide, 50% glycerol.
PuritySupernatant
ImmunogenSynthetic peptide corresponding to residues near the N-terminus in human Histone Deacetylase 6.
SpecificityRecognizes human Histone Deacetylase 6.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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