Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Interferon » Anti -IFN alpha R1 (IFNAR1, FN-alpha-REC, IFNBR, IFRC, Interferon alpha/beta receptor 1)

Anti -IFN alpha R1 (IFNAR1, FN-alpha-REC, IFNBR, IFRC, Interferon alpha/beta receptor 1)


  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.


Clone Host Grade Applications
Monoclonal Rabbit Supernatant B
Interferon alpha receptor 1 (IFN alpha R1) is a class II cytokine receptor that belongs to the type I human interferons (IFNs) family. IFNs plays a role in antiviral, antiproliferative, immunomodulatory, antitumor, and antiparasitic activities by inducing transcription of IFN-stimuated genes (ISGs) through activation of the Jak-STAT pathway. Specifically, IFN alpha R1 is a 135kD signal transducing subunit of the IFN alpha/beta receptor complex (IFN- R) (1). IFN alpha R1 is phosphorylated through PTK- and PKC-mediated phosphorylation, which initiates docking of STAT proteins to IFNs. This leads to activation of STAT proteins by PTK-mediated phosphorylation. The mechanism behind the amplification of IFN alpha R complex mediated transmembrane signaling has been linked to tyrosine phosphorylation on IFN alpha R1 (2).
Catalog #045630
ApplicationsSuitable for use in Western Blot. Other applications have not been tested.
Recommended Dilutions
Western Blot: 1:1000-1:10,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
Clone NoEPR6244
ConcentrationNot determined
FormSupplied as a liquid in PBS, pH 7.2, 0.05% BSA, 0.01% sodium azide, 50% glycerol.
ImmunogenSynthetic peptide corresponding to residues in human IFN alpha R1.
SpecificityRecognizes human IFN alpha R1. Species crossreactivity: Mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

External Links