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You are here:Home » Antibodies » Abs to Ion Transport » Anti -NHERF1 (Na+/H+ Exchanger Regulatory Factor, Na(+)/H(+) Exchange Regulatory Cofactor NHE-RF1, NHERF-1, NHERF, Ezrin-Radixin-Moesin Binding Phosphoprotein 50, EBP50, NPHLOP2, Regulatory Cofactor of Na(+)/H(+) Exchanger, Sodium-hydrogen Exchanger Regulatory

Anti -NHERF1 (Na+/H+ Exchanger Regulatory Factor, Na(+)/H(+) Exchange Regulatory Cofactor
NHE-RF1, NHERF-1, NHERF, Ezrin-Radixin-Moesin Binding Phosphoprotein 50, EBP50, NPHLOP2,
Regulatory Cofactor of Na(+)/H(+) Exchanger, Sodium-hydrogen Exchanger Regulatory

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IP IH IC FC
NHERF1 is a sodium/hydrogen exchanger regulatory cofactor. It interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. NHERF1 also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. It localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in NHERF1 result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this protein is implicated in breast cancer (1).
Catalog #045640
ApplicationsSuitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry and Flow Cytometry. Other applications have not been tested.
Recommended Dilutions
Western Blot: 1:10,000-1:50,000
Immunoprecipitation: 1:10-1:100
Immunohistochemistry: 1:50-1:100
Immunocytochemistry: 1:100-1:250
Flow cytometry: 1:100-1:500
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
Clone NoEPR5563
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in PBS, pH 7.2, 0.05% BSA, 0.01% sodium azide, 50% glycerol.
PuritySupernatant
ImmunogenSynthetic peptide corresponding to residues near the C-terminus of human NHERF1.
SpecificityRecognizes human NHERF1. Species crossreactivity: Mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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