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You are here:Home » Antibodies » Abs to RNA Processing » Anti -RAE1 (MIG14, mRNA Export Factor, mRNA-associated Protein mrnp 41, Mnrp41, MRNP41, FLJ30608, MGC126076, MGC117333, MGC126076, MGC126077)

Anti -RAE1 (MIG14, mRNA Export Factor, mRNA-associated Protein mrnp 41, Mnrp41, MRNP41,
FLJ30608, MGC126076, MGC117333, MGC126076, MGC126077)

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IH
Mutations in the Schizosaccharomyces pombe RAE1 and Saccharomyces cerevisiae Gle2 have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that RAE1 are involved in RNA export. It is a homolog of yeast Rae1. It contains four WD40 motifs and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm.RAE1 is thought to be involved in nucleocytoplasmic transport and directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton.
Catalog #045649
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications have not been tested.
Recommended Dilutions
Western Blot: 1:1000-1:10,000
Immunohistochemistry: 1:100-1:250
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
Clone NoEPR6923
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in PBS, pH 7.2, 0.05% BSA, 0.01% sodium azide, 50% glycerol.
PuritySupernatant
ImmunogenSynthetic peptide corresponding to residues in human RAE1.
SpecificityRecognizes human RAE1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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