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You are here:Home » Antibodies » Abs to Translation Initiation Factors » Anti -AGO4 (Protein Argonaute-4, Argonaute4, hAgo4, Eukaryotic Translation Initiation Factor 2C 4, eIF-2C 4, eIF2C 4, EIF2C4, AGO4, KIAA1567)

Anti -AGO4 (Protein Argonaute-4, Argonaute4, hAgo4, Eukaryotic Translation Initiation
Factor 2C 4, eIF-2C 4, eIF2C 4, EIF2C4, AGO4, KIAA1567)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E
AGO4 also known as EIF2C4 is involved in regulation of gene silencing via small RNA's such as siRNA and miRNA. This protein contains both a PAZ and a PIWI domain characteristic of Argonaute family of proteins. Functionally Ago4 is the catalytic component of the RNA-induced silencing complex (RISC). As part of this multi-protein complex, Ago4 interacts with miRNAs to help mediate translational repression of targeted messages.
Catalog #123060
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
AA SequenceMEALGPGPPASLFQPPRRPGLGTVGKPIRLLANHFQVQIPKIDVYHYDVDIKPEKRPRRVNREVVDTMVRHFKMQIFGDRQPGYDGKRNMYTAHPLPIGR
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a,k
Clone No4G3
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein A affinity chromatography.
ImmunogenPartial recombinant protein corresponding to aa1-101 from human EIF2C4 (NP_060099) with GST tag. MW of the GST tag alone is 26kD.
SpecificityRecognizes human EIF2C4.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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