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You are here:Home » Antibodies » Abs to Protein Kinases » Anti -AKAP12 (A-kinase Anchor Protein 12, AKAP-12, A-kinase Anchor Protein 250 kDa, AKAP 250, Gravin, Myasthenia Gravis Autoantigen, AKAP250, DKFZp686M0430, DKFZp686O0331, FLJ20945, FLJ97621)

Anti -AKAP12 (A-kinase Anchor Protein 12, AKAP-12, A-kinase Anchor Protein 250 kDa, AKAP
250, Gravin, Myasthenia Gravis Autoantigen, AKAP250, DKFZp686M0430, DKFZp686O0331,
FLJ20945, FLJ97621)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternate splicing of this gene results in many isoforms that localize to the centrosome and the Golgi apparatus, and interact with numerous signaling proteins from multiple signal transduction pathways. These signaling proteins include type II protein kinase A, serine/threonine kinase protein kinase N, protein phosphatase 1, protein phosphatase 2a, protein kinase C-epsilon and phosphodiesterase 4D3.
Catalog #123132
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
AA SequenceVPEDDGHALLAERIEKSLVEPKEDEKGDDVDDPENQNSALADTDASGGLTKESPDTNGPKQKEKEDAQEVELQEGKVHSESDKAITPQAQEELQKQERESAKSELTES
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b,k
Clone No1C5
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein A affinity chromatography.
ImmunogenPartial recombinant corresponding to aa1675-1782 from AKAP12 (NP_005091) with GST tag. MW of the GST tag alone is 26kD.
SpecificityRecognizes human AKAP12.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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