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You are here:Home » Antibodies » Abs to Golgi Proteins » Anti -ARAP3 (Arf-GAP with Rho-GAP Domain, ANK Repeat and PH Domain-containing Protein 3, Centaurin-delta-3, Cnt-d3, CENTD3, FLJ21065)

Anti -ARAP3 (Arf-GAP with Rho-GAP Domain, ANK Repeat and PH Domain-containing Protein 3,
Centaurin-delta-3, Cnt-d3, CENTD3, FLJ21065)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
ARAP3, also known as Centaurin-delta-3, is a protein with an Arf-GAP domain, three PH domains, a Ras-associating domain, a Rho-GAP domain and a SAM (sterile alpha motif) domain. ARAP3 is a phosphatidylinositol-3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. It is activated by phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding and can be activated by phosphatidylinositol-3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. ARAP3 acts on ARF6, RAC1, RHOA and CDC42 and also plays a role in the internalization of anthrax toxin.
Catalog #123459
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
AA SequenceVEPPSSLPIRPCGDYTTGGPCPCSFQ
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b,k
Clone No1D6
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein A affinity chromatography.
ImmunogenFull length recombinant corresponding to aa49-75 from human CENTD3 (AAH09968) with GST tag. MW of the GST tag alone is 26kD.
SpecificityRecognizes human CENTD3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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